We Are Committed to Your Health

Our doctors are on call 24/7. Same Day Appointments Available.

Main Street Physicians is now Accepting

New Patients 

We can serve you in these settings:


Primary Care, Family Medicine, and Specialty Clinics specializing in meeting the health needs of seniors, and serving all ages

Physician services for Assisted Living and Skilled Nursing Facility residents at Main Street and select partner facilities.


Personalized wellness plans and check-ups are part of the extra special care you can expect.  That means seeing you before there is a problem as well as when there is.  Scheduled follow-up visits are vital to ensure that your health issues are thoroughly addressed.

Our services are integrated

No more multiple phone calls! With Pharmacy, Therapy, Medical Supplies, Rehab, Ambulance, and more, you save time and worry as we coordinate your care.

Care Available Wherever You Are

When you’re away from home, your doctor is not far away. With our statewide network of primary care offices and electronic health records, you can visit any of our many locations for the same personal healthcare you are used to. With our eVisit service, you can skip the office visit altogether and get the care you need no matter where you are.

You’ll get the optimal diagnoses and treatment with our team approach.  No need to go elsewhere for a second opinion!  Our team of over fifty practitioners confers with each other to provide you with the best, most-informed care, from multiple perspectives

Our comprehensive approach to wellness guarantees you an extraordinary experience!  Main Street Physicians Care’s broad array of health services, delivers the highest level of pro-active, patient care.

Your Health Starts Here

Flexible appointments and urgent care.

Or call — (803) 451-6133

"Through our interventions, patients are engaged in a shared decision-making process, and are empowered to be in control of their treatment."

Dr. Gregory A. Compton


Better Health Care is Our Mission

24/7 service. Same Day Appointments are Available.