Call Center

Please feel free to contact our friendly reception staff with any general or medical enquiry.

(888) 695-2483

Our Team

Qualified doctors and nurse practitioners available seven days a week, view our locations to make appointment. (Hours can vary between locations)

View Locations

Types of Services

  • In Office Visits
  • Telehealth Visits

Improving The Quality Of Your
Life Through Better Health.

Our goal is to deliver quality of care in a courteous, respectful, and compassionate manner. We hope you will allow us to care for you and to be the first and best choice for healthcare.

Find A Doctor

As Main Street Physicians continues to grow in response to the needs of our communities, we recognize that health care should not be a reaction to an illness but a priority for taking a proactive approach in staying as healthy as possible.

We will work with you to develop individualized care plans, including managing chronic diseases. We are committed to being the region's premier healthcare network providing patient-centered care inspiring clinical and service excellence.

  • We conduct a range of tests to help us work out why you're not feeling well and determine the right treatment for you.
  • Our expert doctors, nurses, and allied health professionals manage patients with a broad range of medical issues.
  • We offer our patients a wide range of care and support, from diagnosis to treatment and rehabilitation.

Main Street Physicians Has Improved The Lives Of Patients Throughout South Carolina By Providing A Pathway Toward A Healthier Future.

We are committed to providing quality healthcare access for all patients with our proactive approach to wellness. Please call or visit a Main Street Physicians' office today with any questions you may have.




Trusted Medical Treatment


Telehealth Help Available 24/7








Affordable Prices For All Patients


Quality Care For Every Patient

We hope you will allow us to care for you and strive to be the first and best choice for healthcare. Contact Us For More Information

Meet Our Providers

Our administration and support staff all have exceptional people skills and trained to assist you with all medical enquiries.

Inspiring Stories!

“Nate and his team are amazing. I've never had better experiences at a medical practive, from check in to check out. If you're looking for a team of medical professionals in Columbia, I 100% recommend Main Street Physicians”

“Awesome & friendly staff & doctor! This place makes you feel warm & welcomed here & Dr.Nate Stocker was awesome & helpful. He was really concerned about my problems & wanted to help. This is a doctor that really truly cares & does what he can to help! I'm really glad I found this place.”

“The office staff are super sweet, and my nurse practitioner (Shelley Simmons) is awesome! They also accept medicaid which is a huge relief for me. If you go here, do be mindful that they are actually down an alley on main street, so the office might be slightly challenging to find the first time you go. I was actually a little late for my first appointment but they were very understanding. Best PCP I've ever had!”

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